Confounding factors in vesicle uptake studies using fluorescent lipophilic membrane dyes
نویسندگان
چکیده
منابع مشابه
Confounding factors in vesicle uptake studies using fluorescent lipophilic membrane dyes
Small extracellular vesicles (sEVs) such as exosomes are nanocarriers of proteins, RNAs and DNAs. Isolation of pure sEV populations remains challenging, with reports of protein and lipoprotein contaminants in the isolates. Cellular uptake - a cornerstone for understanding exosome and sEV function - is frequently examined using lipophilic dyes such as PKH67 or CellMask to label the vesicles. In ...
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ژورنال
عنوان ژورنال: Journal of Extracellular Vesicles
سال: 2017
ISSN: 2001-3078
DOI: 10.1080/20013078.2017.1388731